Viscosupplements such as Hyalgan, Synvisc, Orthovisc (Sodium Hyaluronate) , Supartz and Euflexxa are used to treat osteoarthritis of the knee. They are administered as injections in the knee joint once a week for one to five weeks. In some patients these medications provide long lasting relief of pain. If you have pain in the knee from osteoarthritis our rheumatologists will be happy to discuss whether viscosupplements are right for you.